Published on 06.02.2020
Established in 2007 as a Scientific cooperation foundation, the Imagine Institute of Genetic Diseases was awarded the French label of excellence “University Hospital Institute” in 2011 by the French Government, with the Paris Public Hospitals Group (AP-HP), INSERM and University of Paris as institutional public partners. Imagine Institute is an interdisciplinary research centre composed of 24 research labs, 4 adjunct laboratories, 25 rare diseases reference centers and 13 cutting-edge research facilities.
The vision of the institute is to integrate research into clinical practice in order to better understand genetic diseases with unmet medical needs, and to propose and validate diagnostic and therapeutic approaches. This vision can be considered according to four core missions: patient-focused research; innovative care; education and training; and technology transfer. This project builds on a critical mass of experts – 850 scientists, medical doctors, technicians, postdocs, PhD students, paramedical personnel, and therapeutic innovation professionals – established, all in one place in the Imagine building within the Necker-Enfants malades hospital campus (Université de Paris), which takes care of patients and their families to provide them with the diagnostic and therapeutic solutions.
Imagine is recruiting outstanding and enthusiastic students to its International PhD programme. These students will work in an international institute with more than 35 nationalities represented with upto- date facilities and in a multi-disciplinary and stimulating scientific environment. The training program presents opportunities in genetics, immunology, infectious diseases, haematology, nephrology, developmental defects, metabolic diseases, encephalopathies, cardiology, clinical bioinformatics, dermatology and gastroenterology within the research groups of Imagine and associated labs (Annex 1). An individual thesis advisory committee will provide personal feedback, guidance and mentorship for every student.
Four positions are open for this call. They include a salary (€ 2000 per month net salary) for 3 years.
The person in charge of the programme is Dr. Frédéric Rieux-Laucat.
List of the 24 research laboratories and projects for the call :
- Autoimmunity Through multi-OMICS analysis (ATOMICS)
- Deciphering proteoglycan impairment in skeletal dysplasia with multiple dislocations and development of new therapeutic approach
- DNA damage/repair coupling as a safeguard against genetic instability: V(D)J recombination as a paradigm
- Inborn errors of immunity to Human Papillmomaviruses
- Iron homeostasis in Friedreich ataxia and Neurodegeneration with Brain Iron Accumulation
- Single cell based characterization of inflammatory pathways and therapeutic targets in inflammatory bowel diseases
- Programmed Cell Death of Cajal-Retzius cells in the maturation of functional and dysfunctional cortical circuits
- Genetic and pathological mechanisms involved in cerebellar developmental defects
- Erythropoietin deactivation of red blood cell elimination: implications in ß-thalassemia and transfusion
- Integrated gene and proteomic signatures in Darier and Hailey‐Hailey diseases
- Graph representation learning on clinical & multi-omics longitudinal data for improved rare-diseases diagnosis and patient-stratification
- Molecular and physiological targets for focal cortical dysplasia (FCD)
- Applicants should hold an MSc with a strong background in biological sciences from a non-French university.
- Research projects proposed by Imagine research laboratories
- Applicants have to select one project and contact the laboratory
- Applicants and supervisors apply together to the call. The application should include:
- CV with references
- Letter of motivation
- Letter from a previous supervisor
- Project (2 pages maximum)
- Applications will be sent by the laboratory by email to : : email@example.com
- Application deadline for the current round is April 27th 2020
Application procedure there are 3 steps in the selection process:
- First step: find a host laboratory. Available labs and their projects will be posted on the web.
- Second step : submit complete application in collaboration with host lab by March 27th. Applications will be reviewed by a scientific committee composed of internal and external scientific experts.
- Third step: 8 short-listed candidates will be invited for an interview week at Imagine Institute from 22th to 26th of June.
Upon acceptance, students will be required to enrol to the doctoral school of Université de Paris.
All PhD students are expected to start by November 2nd.