Yves Ville


Yves Ville
  • Laurent Salomon
  • Julien Stirnemann
  • Marianne Leruez
  • Alexandre Lapillone
  • Laurence Bussières

Best publications

Malan V,  Effect of Cell-Free DNA Screening vs Direct Invasive Diagnosis on Miscarriage Rates in Women With Pregnancies at High Risk of Trisomy 21: A Randomized Clinical Trial. JAMA. 2018 2018 Aug 14;320(6):557-565.

Dorsi M,  Prenatal factors associated with neonatal survival of infants with congenital chylothorax. J Perinatol. 2018 2018 Jan;38(1):31-34.

Leruez-Ville M,  In utero treatment of congenital cytomegalovirus infection with valacyclovir in a multicenter, open-label, phase II study. Am J Obstet Gynecol. 2016 2016 Oct;215(4):462.e1-462.e10.

Desveaux C,  Identification of Symptomatic Fetuses Infected with Cytomegalovirus Using Amniotic Fluid Peptide Biomarkers. PLoS Pathog. 2016 2016 Jan 25;12(1):e1005395.

Malan V,  A French Approach to Test Fetuses with Ultrasound Abnormalities Using a Customized Microarray as First-Tier Genetic Test. Cytogenet Genome Res. 2015 2015;147(2-3):103-10.

See all the publications of the laboratory

See all the publications of the Imagine Institute



This multidisciplinary team aims at improving overall outcome of infants through multidisciplinary prenatal management of patients with congenital abnormalities.

The team works on intrauterine surgery of fetal malformations, treatment of fetal CMV infection, fetal phenotyping by ultrasound and MRI, and artificial intelligence in prenatal diagnosis.

Our objectives:

  • Bring accurate phenotypical description of fetuses affected by congenital and developmental anomalies and improve phenotype-genotype correlations
  • Develop innovative pre and postnatal diagnostic and therapeutic procedures in a multidisciplinary joined approach to either cure or limit the progressive damage caused by selected severe congenital abnormalities
  • Develop sharing of experience between peers and other professionals and improve patients’ information and education.

Intrauterine endoscopic repair of fetal myelo-meningocele