About
The Castleman team is dedicated to the study of all forms of Castleman diseases and I serve as scientific coordinator of the French national Reference for Castleman diseases. The team includes a post-doctoral fellow, two PhD students, and one Master’s student. Our research focuses on the genomic drivers and stromal involvement in Unicentric Castleman disease and their links to autoimmune and neoplastic complications, such as follicular dendritic cell sarcoma.
Additionally, we aim to develop novel diagnostic and therapeutic tools for HHV8+ multicentric Castleman disease using in vitro and ex vivo models, while studying the disease's pathophysiology with a focus on viral-induced genomic instability and the occurrence of primary effusion lymphoma.
2020Journal (source)J Allergy Clin Immunol