IRF4 haploinsufficiency in a family with Whipple's disease.
Guérin A,Kerner G,Marr N,Markle J,Fenollar F,Wong N,Boughorbel S,Avery D,Ma C,Bougarn S,Bouaziz M,Béziat V,Della Mina E,Oleaga-Quintas C,Lazarov T,Worley L,Nguyen T,Patin E,Deswarte C,Martinez-Barricarte R,Boucherit S,Ayral X,Edouard S,Boisson-Dupuis S,Rattina V,Bigio B,Vogt G,Geissmann F,Quintana-Murci L,Chaussabel D,Tangye S,Raoult D,Abel L,Bustamante J,Casanova J
Source :
Elife
2018 Mar 14
Pmid / DOI:
29537367
Abstract
Most humans are exposed to (Tw). Whipple's disease (WD) strikes only a small minority of individuals infected with Tw (