Publications and ressources

Human genetic and immunological determinants of critical COVID-19 pneumonia.

Qian Zhang, Paul Bastard, Aurélie Cobat, Jean-Laurent CASANOVA , Anna-Lena Neehus, Anne Puel, Bertrand Boisson, Daniela Matuozzo, Emmanuelle Jouanguy, Jean-Laurent CASANOVA , Jérémie Rosain, Jeremy Manry, Laurent Abel , Lucia Victoria Erazo, Quentin Philippot, Romain Levy, Shen-Ying Zhang, Stéphanie Boisson-Dupuis, Tom Le Voyer, Vivien Beziat

Source : Nature

2022 jan 28

Pmid : 35090163

Novel genome-editing-based approaches to treat motor neuron diseases: Promises and challenges.

Annarita Miccio , Panagiotis Antoniou, Sorana CIURA, Edor Kabashi

Source : Mol Ther

2022 jan 5

Pmid : 33823304

Dystrophic epidermolysis bullosa pruriginosa: a new case series of a rare phenotype unveils skewed Th2 immunity.

Source : J Eur Acad Dermatol Venereol

2022 jan 1

Pmid : 34543471

Trial of Spesolimab for Generalized Pustular Psoriasis.

Hervé Bachelez

Source : N Engl J Med

2021 déc 23

Pmid : 34936739

Trial of Spesolimab for Generalized Pustular Psoriasis.

Hervé Bachelez

Source : N Engl J Med

2021 déc 23

Pmid : 34936739

Drug Repurposing Reveals mTOR Inhibition as a Promising Strategy for Epidermolysis Bullosa Simplex.

Hélène Ragot, Alain Hovnanian

Source : J Invest Dermatol

2021 déc 16

Pmid : 34924185

A CBF decrease in the left supplementary motor areas: New insight into postoperative pediatric cerebellar mutism syndrome using arterial spin labeling perfusion MRI.

Jennifer Boisgontier, Ludovic Fillon, Caroline Rutten , Ana Saitovitch, Hervé Lemaître, Thomas Blauwblomme, Alice Vinçon-Leite, Monica Zilbovicius , Nathalie Boddaert

Source : J Cereb Blood Flow Metab

2021 déc 1

Pmid : 34259072

Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction.

Baptiste LAMARTHÉE, Soëli CHARBONNIER, Tifanie BLEIN, Emmanuel Martin, Matthias Titeux, Marianne DELVILLE, Hélène VINÇON, Emmanuelle SIX, Sylvain Latour, Marina Cavazzana, Isabelle André, Julien ZUBER

Source : Nat Commun

2021 nov 8

Pmid : 34750385

Pustular psoriasis: Molecular pathways and effects of spesolimab in generalized pustular psoriasis.

Hervé Bachelez

Source : J Allergy Clin Immunol

2021 oct 20

Pmid : 34678325

Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A.

Alice Lepelley, Marie-Louise Frémond, Luís Seabra, Yanick Crow

Source : The journal of experimental medicine 2021

2021 oct 4

Pmid : 34387651

Immunity to EBV as revealed by immunedeficiencies.

Sylvain Latour

Source : Curr Opin Immunol

2021 oct 1

Pmid : 33989894

SARS-CoV-2 infection inducing severe flare up of Deficiency of Interleukin Thirty-six (IL-36) Receptor Antagonist (DITRA) resulting from a mutation invalidating the activating cleavage site of the IL-36 receptor antagonist.

Hervé Bachelez

Source : J Clin Immunol

2021 oct 1

Pmid : 34176064

Netherton syndrome subtypes share IL-17/IL-36 signature with distinct IFN-α and allergic responses.

Claire Barbieux, Mathilde Bonnet des Claustres, Olivier Gouin, Florent Leturcq, Christine Bole, Vivien Beziat, Alain Hovnanian

Source : J Allergy Clin Immunol

2021 sep 17

Pmid : 34543653

A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis.

Camille DE CEVINS, Marine LUKA, Sonia MEYNIER, Aude Magerus, Laura BARNABEI, Alexandre BOULLE, Marie-Claude Stolzenberg, Vithura PIRABAKARAN, Quentin Riller, Ghaith ABDESSALEM, Mohammed ZARHRATE, Mélanie Parisot, Camille BRUNAUD, Shen-Ying Zhang, Jean-Laurent CASANOVA , Brigitte Bader-Meunier, Isabelle Melki, Damien Bonnet, Slimane Allali, Loïc de Pontual, Alain Fischer, Frédéric Rieux-Laucat

Source : Med (N Y)

2021 sep 10

Pmid : 34414385

Intestinal immunoregulation: lessons from human mendelian diseases.

Fabienne CHARBIT-HENRION, Marianna Parlato, Georgia MALAMUT, Frank RUEMMELE, Nadine CERF-BENSUSSAN

Source : Mucosal Immunol

2021 sep 1

Pmid : 33859369