Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients.

Gervais A,Rovida F,Avanzini M,Croce S,Marchal A,Lin S,Ferrari A,Thorball C,Constant O,Le Voyer T,Philippot Q,Rosain J,Angelini M,Pérez Lorenzo M,Bizien L,Achille C,Trespidi F,Burdino E,Cassaniti I,Lilleri D,Fornara C,Sammartino J,Cereda D,Marrocu C,Piralla A,Valsecchi C,Ricagno S,Cogo P,Neth O,Marín-Cruz I,Pacenti M,Sinigaglia A,Trevisan M,Volpe A,Marzollo A,Conti F,Lazzarotto T,Pession A,Viale P,Fellay J,Ghirardello S,Aubart M,Ghisetti V,Aiuti A,Jouanguy E,Bastard P,Percivalle E,Baldanti F,Puel A,MacDonald M,Rice C,Rossini G,Murray K,Simonin Y,Nagy A,Barzon L,Abel L,Diamond M,Cobat A,Zhang S,Casanova J,Borghesi A

Source :

2023 Jun 22

Pmid / DOI:

37347462

Abstract

Mosquito-borne West Nile virus (WNV) infection is benign in most individuals but can cause encephalitis in

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