Presentation
Scientific Publications
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2025
TYRA-300, an FGFR3-selective inhibitor, promotes bone growth in two FGFR3-dri..., American Society for Clinical Investigation
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2024
Low-dose infigratinib increases bone growth and corrects growth plate abnorma..., J Bone Miner Res
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2023
Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mi..., American Society for Clinical Investigation
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2021
Prevention of guanylyl cyclase–B dephosphorylation rescues achondroplastic dw..., American Society for Clinical Investigation
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2021
An Fgfr3-activating mutation in immature murine osteoblasts affects the appen..., Dis Model Mech
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2020
FGFR3 in Periosteal Cells Drives Cartilage-to-Bone Transformation in Bone Rep..., Stem Cell Reports
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2020
Fgfr3 Is a Positive Regulator of Osteoblast Expansion and Differentiation Dur..., J Bone Miner Res
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2019
Animal models of craniosynostosis., Neurochirurgie
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2017
Constitutively-active FGFR3 disrupts primary cilium length and IFT20 traffick..., Hum Mol Genet
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2017
Achondroplasia: Development, pathogenesis, and therapy., Dev Dyn
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2016
Meckel's and condylar cartilages anomalies in achondroplasia result in defect..., Hum Mol Genet
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2016
Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwar..., J Clin Invest
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2014
FGFR3 mutation causes abnormal membranous ossification in achondroplasia., Hum Mol Genet
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2012
Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse mode..., Am J Hum Genet
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2012
An activating Fgfr3 mutation affects trabecular bone formation via a paracrin..., Hum Mol Genet
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2011
A novel tyrosine kinase inhibitor restores chondrocyte differentiation and pr..., Hum Mol Genet