À propos
I am an INSERM-appointed Assistant Professor at the Imagine Institute in the Laboratory of Human Genetics of Infectious Diseases (HGID). My research focuses on the human genetic contribution to the natural history of mycobacterial and viral infections. I completed a medical degree with a diploma of specialized studies of Public Health at the French Paris Descartes University in 2009. During my medical training, I decided to extend my work to research and joined the HGID laboratory (led by Dr Laurent Abel and Pr Jean-Laurent Casanova) in Paris, France, as a PhD student in Genetic Epidemiology. I began studying the human genetic basis of the early phase of Mycobacterium tuberculosis (Mtb) infection. During my postdoctoral training at McGill University, Canada (supervised by Pr Erwin Schurr), I studied the genetic components of the second most common mycobacterial infection, leprosy. When I returned to the HGID laboratory in 2013, I began to work on viral diseases. In 2016, I was recruited as an INSERM researcher in the HGID laboratory, where I lead a research team focusing on computational genetics of human infections. The onset of the COVID-19 pandemic provided me with a new challenge, and I made major contributions to the discovery of the first genetic and immunological causes of life-threatening COVID-19 pneumonia. . My expertise lie at the interface of genetic epidemiology, biostatistics and bioinformatics.
Projet scientifique
My research program aims to identify the human genetic determinants of susceptibility and resistance to infectious diseases through the analysis of large-scale genomic datasets. It combines the development of innovative statistical and computational methods with their application to well-phenotyped cohorts, with a particular focus on viral and mycobacterial infections.