Paul BASTARD | Institut Imagine

Présentation

Dr, PI, MCU-PH

Paul BASTARD

Génétique humaine des maladies infectieuses

Contact :

paul.bastard@institutimagine.org

À propos

Publications scientifiques

Publications

2026

Expanding the clinical spectrum of RNU4ATAC-opathies: More frequent and diver..., Elsevier BV
2026

High Nasopharyngeal SARS-CoV-2 Load and Delayed Clearance in Hospitalized Pat..., J Infect Dis
2026

High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with ..., medRxiv
2026

Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephali..., J Hum Immun
2026

The STING HAQ haplotype and clinical non-penetrance in COPA syndrome., J Exp Med
2026

An unusual case of RIPK1-related immunodeficiency: The importance of a timely..., Pediatr Allergy Immunol
2025

Autoantibodies neutralizing type I IFNs in patients with fulminant herpes sim..., J Exp Med
2025

Novel de novo dominant PSMB10 varian..., Rockefeller University Press
2025

Intronic branchpoint-to-acceptor variants underlying inborn errors of immunity., J Hum Immun
2024

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med
2024

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med
2024

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A
2024

Tuberculosis in otherwise healthy adults with inherited TNF deficiency., Nature
2024

Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency., Nature
2024

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 o..., J Clin Invest
2024

The immunopathological landscape of human pre-TCRα deficiency: From rare to c..., Science
2024

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med
2023

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol
2023

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med
2023

Rare predicted loss-of-function variants of type I IFN immunity genes are ass..., Genome Med
2023

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell
2022

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneu..., J Exp Med
2022

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A
2022

Human genetic and immunological determinants of critical COVID-19 pneumonia., Nature
2021

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol
2021

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol
2021

Association of rare predicted loss-of-function variants of influenza-related ..., J Clin Invest
2021

Polyclonal expansion of TCR Vbeta 21.3 CD4 and CD8 T cells is a hallmark of M..., Sci Immunol
2021

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med
2020

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science
2020

Autoantibodies against type I IFNs in patients with life-threatening COVID-19., Science
2019

Severe influenza pneumonitis in children with inherited TLR3 deficiency., J Exp Med
2019

Inherited IL-18BP deficiency in human fulminant viral hepatitis., J Exp Med

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Présentation

À propos

Publications scientifiques

Expanding the clinical spectrum of RNU4ATAC-opathies: More frequent and diver..., Elsevier BV

High Nasopharyngeal SARS-CoV-2 Load and Delayed Clearance in Hospitalized Pat..., J Infect Dis

High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with ..., medRxiv

Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephali..., J Hum Immun

The STING HAQ haplotype and clinical non-penetrance in COPA syndrome., J Exp Med

An unusual case of RIPK1-related immunodeficiency: The importance of a timely..., Pediatr Allergy Immunol

Autoantibodies neutralizing type I IFNs in patients with fulminant herpes sim..., J Exp Med

Novel de novo dominant PSMB10 varian..., Rockefeller University Press

Intronic branchpoint-to-acceptor variants underlying inborn errors of immunity., J Hum Immun

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A

Tuberculosis in otherwise healthy adults with inherited TNF deficiency., Nature

Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency., Nature

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB115:02 o..., J Clin Invest*

The immunopathological landscape of human pre-TCRα deficiency: From rare to c..., Science

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med

Rare predicted loss-of-function variants of type I IFN immunity genes are ass..., Genome Med

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneu..., J Exp Med

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A

Human genetic and immunological determinants of critical COVID-19 pneumonia., Nature

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol

Association of rare predicted loss-of-function variants of influenza-related ..., J Clin Invest

Polyclonal expansion of TCR Vbeta 21.3 CD4 and CD8 T cells is a hallmark of M..., Sci Immunol

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science

Autoantibodies against type I IFNs in patients with life-threatening COVID-19., Science

Severe influenza pneumonitis in children with inherited TLR3 deficiency., J Exp Med

Inherited IL-18BP deficiency in human fulminant viral hepatitis., J Exp Med

Présentation

À propos

Publications scientifiques

Expanding the clinical spectrum of RNU4ATAC-opathies: More frequent and diver..., Elsevier BV

High Nasopharyngeal SARS-CoV-2 Load and Delayed Clearance in Hospitalized Pat..., J Infect Dis

High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with ..., medRxiv

Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephali..., J Hum Immun

The STING HAQ haplotype and clinical non-penetrance in COPA syndrome., J Exp Med

An unusual case of RIPK1-related immunodeficiency: The importance of a timely..., Pediatr Allergy Immunol

Autoantibodies neutralizing type I IFNs in patients with fulminant herpes sim..., J Exp Med

Novel de novo dominant PSMB10 varian..., Rockefeller University Press

Intronic branchpoint-to-acceptor variants underlying inborn errors of immunity., J Hum Immun

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A

Tuberculosis in otherwise healthy adults with inherited TNF deficiency., Nature

Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency., Nature

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 o..., J Clin Invest

The immunopathological landscape of human pre-TCRα deficiency: From rare to c..., Science

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med

Rare predicted loss-of-function variants of type I IFN immunity genes are ass..., Genome Med

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneu..., J Exp Med

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A

Human genetic and immunological determinants of critical COVID-19 pneumonia., Nature

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol

Association of rare predicted loss-of-function variants of influenza-related ..., J Clin Invest

Polyclonal expansion of TCR Vbeta 21.3 CD4 and CD8 T cells is a hallmark of M..., Sci Immunol

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science

Autoantibodies against type I IFNs in patients with life-threatening COVID-19., Science

Severe influenza pneumonitis in children with inherited TLR3 deficiency., J Exp Med

Inherited IL-18BP deficiency in human fulminant viral hepatitis., J Exp Med

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB115:02 o..., J Clin Invest*