Tom LE VOYER | Institut Imagine

Présentation

Tom LE VOYER

Génétique humaine des maladies infectieuses : prédisposition monogénique, Génétique humaine des maladies infectieuses

Contact :

01 42 75 47 53

tom.le-voyer@institutimagine.org

À propos

Publications scientifiques

Publications

2026

High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with ..., medRxiv
2026

Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs..., Nat Immunol
2025

A promoter variant underlying Wiskott-Aldrich syndrome in two kindreds., J Hum Immun
2025

Intronic branchpoint-to-acceptor variants underlying inborn errors of immunity., J Hum Immun
2025

Two different forms of inherited human TCRα chain deficiency., J Hum Immun
2025

Mutations disrupting the kinase domain of IKKα lead to immunodeficiency and i..., J Exp Med
2024

Autoinflammation in patients with leukocytic CBL loss of heterozygosity is ca..., J Clin Invest
2024

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med
2024

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med
2024

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A
2024

Tuberculosis in otherwise healthy adults with inherited TNF deficiency., Nature
2024

Individuals with JAK1 variants are affected by syndromic features encompassin..., J Exp Med
2024

Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency., Nature
2024

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 o..., J Clin Invest
2024

The immunopathological landscape of human pre-TCRα deficiency: From rare to c..., Science
2024

Recombinant IFN-γ1b Treatment in a Patient with Inherited IFN-γ Deficiency., J Clin Immunol
2024

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med
2023

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol
2023

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med
2023

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell
2022

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A
2022

Pulmonary Alveolar Proteinosis and Multiple Infectious Diseases in a Child wi..., J Clin Immunol
2021

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol
2021

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol
2021

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med
2020

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science

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Présentation

À propos

Publications scientifiques

High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with ..., medRxiv

Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs..., Nat Immunol

A promoter variant underlying Wiskott-Aldrich syndrome in two kindreds., J Hum Immun

Intronic branchpoint-to-acceptor variants underlying inborn errors of immunity., J Hum Immun

Two different forms of inherited human TCRα chain deficiency., J Hum Immun

Mutations disrupting the kinase domain of IKKα lead to immunodeficiency and i..., J Exp Med

Autoinflammation in patients with leukocytic CBL loss of heterozygosity is ca..., J Clin Invest

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A

Tuberculosis in otherwise healthy adults with inherited TNF deficiency., Nature

Individuals with JAK1 variants are affected by syndromic features encompassin..., J Exp Med

Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency., Nature

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB115:02 o..., J Clin Invest*

The immunopathological landscape of human pre-TCRα deficiency: From rare to c..., Science

Recombinant IFN-γ1b Treatment in a Patient with Inherited IFN-γ Deficiency., J Clin Immunol

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A

Pulmonary Alveolar Proteinosis and Multiple Infectious Diseases in a Child wi..., J Clin Immunol

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science

Présentation

À propos

Publications scientifiques

High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with ..., medRxiv

Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs..., Nat Immunol

A promoter variant underlying Wiskott-Aldrich syndrome in two kindreds., J Hum Immun

Intronic branchpoint-to-acceptor variants underlying inborn errors of immunity., J Hum Immun

Two different forms of inherited human TCRα chain deficiency., J Hum Immun

Mutations disrupting the kinase domain of IKKα lead to immunodeficiency and i..., J Exp Med

Autoinflammation in patients with leukocytic CBL loss of heterozygosity is ca..., J Clin Invest

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I I..., J Exp Med

Autoantibodies neutralizing type I IFNs underlie severe tick-borne encephalit..., J Exp Med

A sensitive assay for measuring whole-blood responses to type I IFNs., Proc Natl Acad Sci U S A

Tuberculosis in otherwise healthy adults with inherited TNF deficiency., Nature

Individuals with JAK1 variants are affected by syndromic features encompassin..., J Exp Med

Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency., Nature

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 o..., J Clin Invest

The immunopathological landscape of human pre-TCRα deficiency: From rare to c..., Science

Recombinant IFN-γ1b Treatment in a Patient with Inherited IFN-γ Deficiency., J Clin Immunol

Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-..., J Exp Med

Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs n..., Sci Immunol

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis..., J Exp Med

Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria., Cell

The risk of COVID-19 death is much greater and age dependent with type I IFN ..., Proc Natl Acad Sci U S A

Pulmonary Alveolar Proteinosis and Multiple Infectious Diseases in a Child wi..., J Clin Immunol

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life..., Sci Immunol

Autoantibodies neutralizing type I IFNs are present in 4% of uninfected indiv..., Sci Immunol

Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever..., J Exp Med

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19., Science

Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB115:02 o..., J Clin Invest*