About
Passionate about biomedical research and human genetics, I am currently pursuing my PhD at the Institut Imagine within the Laboratory of Ophthalmic Genetics. My work aims to better understand the genetic mechanisms underlying rare eye diseases, with a strong focus on bridging fundamental discoveries and clinical applications, in order to ultimately improve patient care.
Alongside my research activities, I served as President of the Sports Association at Institut Imagine (2024–2025), with the goal of promoting well-being, cohesion, and team spirit through sports initiatives dedicated to researchers and students. I am also Vice-President of Sweet Serotonine, a dance and cultural association at Université Paris Cité. I strongly believe in the importance of balancing scientific rigor, collective engagement, and physical activity.
Scientific project
A new avenue for understanding rare eye diseases
Some families are affected by very early-onset, severe retinal disorders that lead to progressive vision loss from childhood. In several cases, despite extensive genetic testing, no causative gene can be identified. Our work is set in this context.
Discovery of a new gene involved in vision
Through whole-exome sequencing in two unrelated families from our cohort, in collaboration with the European Retinal Disease Consortium, we identified variants in a gene not previously associated with retinal disease.
This gene encodes an RNA helicase, a protein essential for RNA metabolism and involved in innate immunity. Until now, it had mainly been implicated in hematological disorders, with no established link to vision.
From gene to disease
Using complementary cellular approaches and experimental models, we investigate how these variants alter retinal cell function and progressively lead to vision loss.
Opening new perspectives
These findings expand our understanding of RNA helicases and reveal an unexpected role in retinal homeostasis. In the long term, this work may improve genetic diagnosis and open new avenues to better understand—and eventually treat—these rare vision disorders.
