Biallelic germline variants in the hematologic malignancy predisposition gene DDX41 cause retinal dystrophy through dysregulation of retinal homeostasis

Biallelic germline variants in the hematologic malignancy predisposition gene DDX41 cause retinal dystrophy through dysregulation of retinal homeostasis

Mars Z,Zanetti A,Kaminska K,Miyagawa T,Liu D,Antonio A,Arno G,Audo I,Ayuso C,Muhammad Jafar Hussain H,Bao X,Barberán-Martínez P,Bocquet B,Boguszewska-Chachulska A,Condroyer C,David P,Dollfus H,Fares-Taie L,Fernández-Caballero L,García-García G,Michel V,Guerrera C,Jung V,Kessel L,Gioja L,Lin S,Matczynska E,Millán J,Moye A,Martín-Gutiérrez M,Quinodoz M,Robert M,Roger J,Sousa-Luis R,Swafiri S,Teper S,Meunier I,Patat O,Pennesi M,Wadt K,Wang M,Webster A,Yang P,Yumei L,Zeitz C,Rieux-Laucat F,Giraudier S,Chen R,Fica S,Rivolta C,Sebert M,Rozet J,Perrault I

Source :

2026 Jan 30

Pmid / DOI:

10.64898/2026.01.28.26344834