Modeling Parkinson’s pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity

Modeling Parkinson’s pathology in human iPSC dopaminergic neurons uncovers key mechanisms of Lewy body formation and heterogeneity

Mahul-Mellier A,van den Heuvel L,Teixeira M,Boussouf M,Oudinot G,Thonet A,Speri D,Jasiqi Y,Ulrich C,Sheta R,Idi W,Croisier M,Clerc-Rosset S,Blanc J,Knott G,Oueslati A,Lashuel H

Source :

2026 Jul 10

Pmid / DOI:

https://www.science.org/doi/10.1126/sciadv.aed8851