Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndrome

Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndrome

Batignes M,Luka M,Jagtap S,de Cevins C,Nemazanyy I,Leib J,Fali T,Pierga A,Zarhrate M,García-Paredes V,Carbone F,Pérot B,Neven B,Bader-Meunier B,Quartier P,Hully M,Belot A,Lepelley A,Frémond M,Fischer A,Ménager M

Source :

2026 Mar 3

Pmid / DOI:

10.1038/s41467-026-69979-9