Présentation

Contact
Emmanuelle Six est chargée de recherche INSERM à l'Institut Imagine, Paris. Ses travaux sur l'hématopoïèse contribuent à la caractérisation des progéniteurs lymphoïdes humains et à la description d'une déficience immunitaire profonde. Forte de cette expertise en hématologie fondamentale et clinique, Emmanuelle Six mène un projet dédié à l'hématopoïèse humaine et qui lui a permis de développer un projet interdisciplinaire avec d'autres laboratoires.
Ressources & publications
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Journal (source)Blood Adv
Adenylate kinase 2 expression and addiction in T-ALL.
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Journal (source)Nat Med
Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: t...
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Journal (source)Nat Commun
Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced d...
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Journal (source)Nature Biotechnology
Gene signature extraction and cell identity recognition at the single-cell le...
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Journal (source)Cell Mol Immunol
A DL-4- and TNFα-based culture system to generate high numbers of nonmodified...
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Journal (source)Nat Immunol
Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrins...
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Journal (source)JAMA
Outcomes following gene therapy in patients with severe Wiskott-Aldrich syndr...
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Journal (source)Nat Immunol
Single-cell analysis reveals the continuum of human lympho-myeloid progenitor...
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Journal (source)Blood
A combination of cyclophosphamide and interleukin-2 allows CD4+ T cells conve...
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Journal (source)Nat Rev Drug Discov
Gene therapy targeting haematopoietic stem cells for inherited diseases: prog...
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Journal (source)Nat Biotechnol
Gene signature extraction and cell identity recognition at the single-cell le...
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Journal (source)Blood
Clonal tracking in gene therapy patients reveals a diversity of human hematop...
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Journal (source)Blood
Clonal tracking in gene therapy patients reveals a diversity of human hematop...
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Journal (source)Stem Cells
Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 cul...
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Journal (source)Cell Death Dis
AK2 deficiency compromises the mitochondrial energy metabolism required for d...
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Journal (source)Hum. Gene Ther.
Gene Therapy for X-Linked Severe Combined Immunodeficiency: Where Do We Stand?
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Journal (source)Mol Ther Methods Clin Dev
A Nontoxic Transduction Enhancer Enables Highly Efficient Lentiviral Transduc...