Résultat de recherche

Innate immune cells, major actors of sickle cell disease pathophysiology.

Olivier Hermine, Thiago Trovati Maciel

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A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease.

Olivier Hermine, Thiago Trovati Maciel

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Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin.

Francine Côté, Olivier Hermine

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FAS and RAS related Apoptosis defects: From autoimmunity to leukemia.

Frédéric Rieux-Laucat

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Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation.

Frédéric Rieux-Laucat

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Autoimmune lymphoproliferative syndrome with somatic Fas mutations.

Frédéric Rieux-Laucat

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Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity.

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Inactivation of the Fas gene by Alu insertion: retrotransposition in an intron causing splicing variation and autoimmune lymphoproliferative syndrome.

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Inherited and somatic CD3zeta mutations in a patient with T-cell deficiency.

Alain Fischer

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FAS-L, IL-10, and double-negative CD4- CD8- TCR alpha/beta+ T cells are reliable markers of autoimmune lymphoproliferative syndrome (ALPS) associated with FAS loss of function.

Frédéric Rieux-Laucat

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Reduced expression of FOXP3 and regulatory T-cell function in severe forms of early-onset autoimmune enteropathy.

Nadine CERF-BENSUSSAN

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A survey of 90 patients with autoimmune lymphoproliferative syndrome related to TNFRSF6 mutation.

Frédéric Rieux-Laucat

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