Chris OTTOLENGHI

PU-PH | Agnès Rötig

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Chris OTTOLENGHI

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Chris, MD, PhD and PU-PH, is a Professor of Biochemistry and Molecular Biology at the University of Paris Centre with hospital appointment in the Metabolomics Unit of the Department of Biology, Physiology and Genetics at the Hospital Necker-Enfants Malades. After training in human genetics and bioinformatics, he took a 5-year post-doctoral fellowship on mouse models of sex reversal and premature ovarian failure in the Department of Genetics of the National Institute on Aging (NIA, NIH) in Baltimore USA.

 

His current research interests include :

 

1) Discovery and biochemical characterization of novel genes involved in inherited metabolic disorders,

 

2) Study of amino acid metabolic pathways modulating Krebs cycle oncometabolic dysfunctions,

 

3) Mass spectrometry metabolomics and flux analyses for the robust quantitation of small molecules of clinical interest.

Activite de laboratoire

Research: a scientific adventure

Our goal: to better understand genetic diseases to better treat them.