My research is aimed at understanding the genetic causes and developmental mechanisms underlying craniofacial, cardiac and neurodevelopmental disorders. Working closely with clinicians consulting patients with rare disorders at the Necker children's hospital, my group uses whole genome sequencing techniques to identify novel causes of disease. We use in vitro and in vivo models (zebrafish, mice), generated with CRISPR/Cas9 genome editing tools, to explore the pathogenicity and developmental consequences of variants identified in patients.

ORCID ID: https://orcid.org/0000-0002-9300-8399