Principal investigators

À l’Institut Imagine, les Principal Investigators sont au cœur de notre dynamique scientifique. Médecins et chercheurs, ils portent des programmes ambitieux dédiés à la compréhension des maladies génétiques et contribuent, chacun à leur manière, à faire émerger des avancées décisives pour les patients et leurs familles.
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Frédéric CAUSERET,
Principal investigator

Fate specification in the developing cerebral cortex

Vivien Béziat
Vivien Beziat,
Principal investigator

Genetics of leukocyte immunity against mucocutaneous oncoviruses

Aurélie Cobat
Aurélie Cobat,
Principal investigator

Computational genetics of infectious diseases

Nadege Bondurand
Nadege Bondurand,
Principal investigator

Neurocristopathies

Portrait Eric Allemand
Eric Allemand,
Principal investigator

Dysregulated RNA processing in rare immuno-hematological disorders

Alice LEPELLEY
Alice Lepelley,
Principal investigator

Understanding innate immune dysregulation in human autoinflammation

Sven Kracker
Sven Kracker,
Principal investigator

Pathological mechanisms underlying primary antibody deficiencies

Portait Paul Bastard
Paul Bastard,
Principal investigator

Autoimmunity to immunity: susceptibility to infections and cancer

Brusson
Mégane Brusson,
Principal investigator

Regulation of erythropoiesis and therapeutic targeting in genetic anemias

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Claire Soudais,
Principal investigator

Development of mouse models for the study of immune deficiencies.

Pascal Amireault
Pascal Amireault,
Principal investigator

Proteostasis dysfunction in thalassemic erythrocytes

Leila MAOUCHE-CHRETIEN
Leila Maouche Chretien,
Principal investigator

Translational research in mastocytosis: new targets and innovative therapies

Photo Amandine Viau
Amandine Viau,
Principal investigator

Cilia-dependent inflammatory signaling in homeostasis and response to injury

Shen-Ying Zhang
Shen-Ying Zhang,
Principal investigator

Human genetic and immunological defects in severe viral disease

Sophie Thomas
Sophie Thomas,
Principal investigator

Genetics and Neurodevelopmental Mechanisms Underlying Ciliopathies

Titeux
Matthias Titeux,
Principal investigator

Development of innovative therapeutic approaches for Epidermolysis Bullosa

Marianna PARLATTO
Marianna Parlato,
Principal investigator

 Immune and epithelial cell homeostasis in intestinal health and disease

Emmanuelle Jouanguy 2022
Emmanuelle Jouanguy,
Principal investigator

Genetic basis of the antiviral skin- or liver-intrinsic immune response

David BOUTBOUL
David Boutboul,
Principal investigator

Pathophysiology of Castleman diseases

Jeremie Rosain
Jeremie Rosain,
Principal investigator

Germline and somatic variants underlying infectious diseases in adults

Jacinta Bustamente
Jacinta Bustamante,
Principal investigator

Genetic and immunological predisposition  in the susceptibility to mycobacterial infections in human

Stéphanie Boisson-Dupuis
Stephanie Boisson-Dupuis,
Principal investigator

Human genetics and immunological determinants of tuberculosis.

Aude MAGERUS
Aude Magerus,
Principal investigator

ALPS (Autoimune lymphoproliferative syndrome) / AIH (Autoimune hepatitis)

Marie Louis Frémond
Marie-Louise Frémond,
Principal investigator

STING-mediated autoinflammation 

Marion COOLEN
Marion Coolen,
Principal investigator

STING-mediated autoinflammation 

Anne Puel carré
Anne Puel,
Principal investigator

Anti-cytokine autoantibodies